Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415350 | 0.86 | HTT (0.75) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9574717 | 0.84 | HTT (0.73) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14430339 | 0.82 | HTT (0.59) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL340937 | 0.82 | HTT (0.69) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL28082064 | 0.81 | HTT (0.68) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10599264 | 0.80 | HTT (0.50) | HTTADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL14430332 | 0.79 | HTT (0.55) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL978857 | 0.78 | HTT (0.64) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL29687865 | 0.78 | ALDH1A1 (0.65) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2844752 | 0.78 | HTT (0.64) | HTTMEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2017-12-28 | — | — | US | disclosed |
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2016-07-21 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190151-A1 | Method of preparing dendritic drugs | MYD88, TLR3, TLR6 | HTT 3647/4885MEN1 3220/4885KMT2A 4308/4885 |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | HTT 3647/4885MEN1 3220/4885KMT2A 4308/4885 |
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | HTT 3647/4885MEN1 3220/4885KMT2A 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.