SCHEMBL14432011

SCHEMBL14432011

CCC(NC(=O)C(F)(F)F)C1CNC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.35
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GBA1 P04062 1/20 0.33
CCRL2 O00421 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.30
CA3 P07451 2/20 0.30
CA5A P35218 2/20 0.30
CA5B Q9Y2D0 2/20 0.30
ELANE P08246 1/20 0.30
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5463207 0.98 EPHX1 (0.34) EPHX1ALDH1A1POLBSMN1; SMN2GBA1
SCHEMBL14432146 0.80 ALDH1A1 (0.31) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL28867577 0.79 GBA1 (0.33) GBA1
SCHEMBL28867575 0.79 GBA1 (0.33) GBA1
SCHEMBL14444080 0.78 CCRL2 (0.35) EPHX1CCRL2IDO1
SCHEMBL9998751 0.76 CCRL2 (0.36) CCRL2IDO1
SCHEMBL9998695 0.72 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2CCRL2KMT2AIDO1
SCHEMBL5458022 0.68 ACHE (0.41) ALDH1A1POLBMEN1KMT2A
SCHEMBL26584928 0.67 EPHX1 (0.37) EPHX1ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL9344459 0.66 SMN1; SMN2 (0.47) EPHX1ALDH1A1POLBSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191333-A1 Antibacterial agents WARNER LAMBERT COMPANY LLC 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191333-A1 Antibacterial agents MRPL21, RPN2, FBL EPHX1 2015/4885ALDH1A1 637/4885POLB 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.