Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.81 |
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307850 | 0.98 | NQO2 (0.85) | NQO2WDR5ALDH1A1TOP1HPGD | |
| SCHEMBL23566334 | 0.92 | NQO2 (0.71) | NQO2WDR5ALDH1A1TOP1HPGD | |
| SCHEMBL14433307 | 0.82 | NQO2 (0.63) | NQO2WDR5ALDH1A1TOP1HPGD | |
| SCHEMBL23566323 | 0.82 | NQO2 (0.58) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL23566322 | 0.80 | NQO2 (0.59) | NQO2ALDH1A1TOP1HPGDCASP1 | |
| SCHEMBL394218 | 0.78 | WDR5 (0.80) | NQO2WDR5ALDH1A1TOP1HPGD | |
| SCHEMBL8973288 | 0.78 | WDR5 (0.80) | NQO2WDR5ALDH1A1TOP1HPGD | |
| SCHEMBL8096354 | 0.78 | NQO2 (0.68) | NQO2LOXL2F2PRSS1PRSS3 | |
| SCHEMBL9254195 | 0.78 | NQO2 (0.61) | NQO2F10LOXL2F2PRSS1 | |
| SCHEMBL537030 | 0.75 | LMNA (0.77) | NQO2WDR5ALDH1A1TOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517893-B2 | Bichalcophenes and their prodrugs as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-14 | — | — | US | claimed |
| EP-1726589-B1 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIV NORTH CAROLINA (US) | 2008-10-15 | — | — | EP | claimed |
| US-20060293540-A1 | Novel bichalcophenes and their prodrugs as antiprotozoal agents | TIDWELL RICHARD R | 2006-12-28 | — | — | US | claimed |
| EP-1726589-A2 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2021127452-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-09-30 | — | — | US | disclosed |
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2010-09-30 | — | — | US | disclosed |
| US-7517893-B2 | Bichalcophenes and their prodrugs as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-14 | — | — | US | disclosed |
| US-7517893-B2 | Bichalcophenes and their prodrugs as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1726589-B1 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIV NORTH CAROLINA (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1792613-A2 | Dicationic compounds which selectively recognize G-quadruplex DNA | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-06-06 | — | — | EP | disclosed |
| US-20060293540-A1 | Novel bichalcophenes and their prodrugs as antiprotozoal agents | TIDWELL RICHARD R | 2006-12-28 | — | — | US | disclosed |
| EP-1726589-A2 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249175-A1 | Dicationic compounds which selectively recognize G-quadruplex DNA | DDB1, DNA2, SSBP1 | NQO2 1541/4885WDR5 1792/4885ALDH1A1 4594/4885 |
| US-20060293540-A1 | Novel bichalcophenes and their prodrugs as antiprotozoal agents | CASP7, DDT, BAD | NQO2 1951/4885WDR5 3551/4885ALDH1A1 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.