Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 20/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 19/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 19/20 | 0.51 |
| ▸ | GABRP | O00591 | 18/20 | 0.51 |
| ▸ | GABRD | O14764 | 18/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 18/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 18/20 | 0.51 |
| ▸ | GABRE | P78334 | 18/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethiprole SCHEMBL27048 | 0.95 | GABRP (0.56) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Ethiprole SCHEMBL15756765 | 0.95 | GABRP (0.56) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL12237528 | 0.92 | GABRP (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Ethiprole SCHEMBL23754762 | 0.91 | GABRP (0.53) | GABRB3GABRA2GABRB2GABRPGABRD | |
| Fipronil SCHEMBL727927 | 0.90 | GABRP (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14094912 | 0.88 | GABRP (0.53) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14389621 | 0.87 | GABRB3 (0.54) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL18165226 | 0.85 | GABRP (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7673675 | 0.85 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL15900786 | 0.84 | GABRP (0.56) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262214-B2 | 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases | MERIAL LIMITED (US) | 2007-08-28 | — | — | US | disclosed |