Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.57 |
| ▸ | GABRD | O14764 | 20/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.57 |
| ▸ | GABRE | P78334 | 20/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12237528 | 0.94 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ethiprole SCHEMBL27048 | 0.90 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ethiprole SCHEMBL15756765 | 0.90 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15900786 | 0.90 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14389621 | 0.88 | GABRB3 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15900783 | 0.87 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ethiprole SCHEMBL23754762 | 0.86 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8790587 | 0.86 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL44222 | 0.86 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Fipronil SCHEMBL2469515 | 0.86 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304467-A1 | FIPRONIL PRODUCTION PROCESS | ADAMA MAKHTESHIM LTD. (IL) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304467-A1 | FIPRONIL PRODUCTION PROCESS | FIP1L1, COXFA4, COXFA4L2 | GABRP 260/4885GABRD 555/4885GABRA1 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.