Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433981 | 1.00 | CHRM2 (0.54) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14434185 | 1.00 | CHRM2 (0.54) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14433984 | 0.84 | EGFR (0.40) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL27056189 | 0.78 | CYP2D6 (0.40) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL27056167 | 0.76 | ADRA2A (0.43) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL19759877 | 0.73 | ALDH1A1 (0.33) | NPSR1 | |
| SCHEMBL14433979 | 0.73 | HTR3A (0.44) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL27056147 | 0.73 | KCNH2 (0.41) | CHRM2ADRA2ACHRM1DRD1SLC6A2 | |
| Mequitazine SCHEMBL18207 | 0.71 | CYP2D6 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Mequitazine SCHEMBL29379090 | 0.71 | CYP2D6 (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085652-A1 | USE OF THE (S) ENANTIOMER OF MEQUITAZINE FOR PREPARING A MEDICAMENT, WHILE AT THE SAME TIME LIMITING GENOMIC TOXICITY | PIERRE FABRE MEDICAMENT (FR) | 2007-08-02 | — | — | WO | disclosed |