Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434879 | 0.91 | L3MBTL1 (0.43) | ALDH1A1POLBCXCR2KDM4EMEN1 | |
| SCHEMBL14434072 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBCXCR2KDM4EMEN1 | |
| SCHEMBL14434874 | 0.91 | CXCR2 (0.46) | ALDH1A1POLBCXCR2SMN1; SMN2LMNA | |
| SCHEMBL14434451 | 0.90 | POLB (0.51) | CASP6ALDH1A1POLBGFERCXCR2 | |
| SCHEMBL5320272 | 0.90 | CXCR2 (0.49) | ALDH1A1GFERCXCR2MEN1GAA | |
| SCHEMBL14434071 | 0.90 | HTT (0.44) | ALDH1A1CXCR2KDM4EMEN1GAA | |
| SCHEMBL5321346 | 0.88 | PTPN5 (0.45) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL5322006 | 0.87 | PTGDR2 (0.40) | ALDH1A1CXCR2KDM4EMCL1MAPT | |
| SCHEMBL14434499 | 0.85 | POLB (0.42) | CASP6ALDH1A1POLBGFERCXCR2 | |
| SCHEMBL14434073 | 0.84 | ALDH1A1 (0.39) | ALDH1A1POLBCXCR2KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |