Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PCTP | Q9UKL6 | 3/20 | 0.38 |
| ▸ | STARD10 | Q9Y365 | 2/20 | 0.38 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.38 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434882 | 0.92 | CXCR2 (0.42) | KMT2AMEN1SMN1; SMN2GPR27CXCR2 | |
| SCHEMBL14434467 | 0.90 | POLB (0.47) | IDH1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14434071 | 0.88 | HTT (0.44) | IDH1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14434073 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTGPR27ACLY | |
| SCHEMBL5320272 | 0.85 | CXCR2 (0.49) | KMT2AMEN1ALDH1A1HTTCXCR2 | |
| SCHEMBL14434883 | 0.85 | CXCR2 (0.43) | KMT2AMEN1ALDH1A1MAPTGPR27 | |
| SCHEMBL14434502 | 0.84 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL14434879 | 0.83 | L3MBTL1 (0.43) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14434072 | 0.83 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL14434444 | 0.82 | POLB (0.46) | KMT2AMEN1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |