Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PTPRG | P23470 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434071 | 0.91 | HTT (0.44) | CXCR2HTTGAAPTGDR2ALDH1A1 | |
| SCHEMBL14434472 | 0.90 | CXCR2 (0.50) | CXCR2HTTGAAGFERPTPRG | |
| SCHEMBL14434876 | 0.90 | CASP6 (0.41) | CXCR2GAAGFERALDH1A1MEN1 | |
| SCHEMBL14434072 | 0.89 | ALDH1A1 (0.47) | CXCR2HTTGAAALDH1A1MEN1 | |
| SCHEMBL14434879 | 0.89 | L3MBTL1 (0.43) | CXCR2GAAALDH1A1MEN1LMNA | |
| SCHEMBL14434874 | 0.88 | CXCR2 (0.46) | CXCR2HTTPTGDR2ALDH1A1LMNA | |
| SCHEMBL5321346 | 0.86 | PTPN5 (0.45) | HTTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5322006 | 0.85 | PTGDR2 (0.40) | CXCR2PTGDR2ALDH1A1 | |
| SCHEMBL14434870 | 0.85 | IDH1 (0.39) | CXCR2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL14434882 | 0.84 | CXCR2 (0.42) | CXCR2MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | claimed |
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |