Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434860 | 0.93 | ALDH1A1 (0.48) | LMNAMAPTMEN1KMT2ACXCR2 | |
| SCHEMBL14434456 | 0.93 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPTMEN1KMT2A | |
| SCHEMBL14434450 | 0.92 | CXCR2 (0.47) | LMNAMAPTMEN1KMT2ACXCR2 | |
| SCHEMBL14434501 | 0.91 | CXCR2 (0.48) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL14434863 | 0.90 | PTPN5 (0.46) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14434454 | 0.90 | CXCR2 (0.41) | LMNAMAPTMEN1KMT2ACXCR2 | |
| SCHEMBL14434502 | 0.89 | ALDH1A1 (0.41) | LMNAMAPTMEN1KMT2ACXCR2 | |
| SCHEMBL14434869 | 0.89 | KMT2A (0.42) | MAPTMEN1KMT2ACXCR2ALDH1A1 | |
| SCHEMBL14434499 | 0.89 | POLB (0.42) | L3MBTL1LMNAMAPTMEN1KMT2A | |
| SCHEMBL14434447 | 0.88 | POLB (0.49) | L3MBTL1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |