Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434456 | 0.94 | L3MBTL1 (0.44) | ALDH1A1MAPTPOLBLMNAMEN1 | |
| SCHEMBL14434450 | 0.94 | CXCR2 (0.47) | ALDH1A1MAPTMETAP2HTTLMNA | |
| SCHEMBL14434873 | 0.93 | L3MBTL1 (0.43) | ALDH1A1MAPTMETAP2HTTLMNA | |
| SCHEMBL14434863 | 0.91 | PTPN5 (0.46) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL14434869 | 0.90 | KMT2A (0.42) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL14434499 | 0.90 | POLB (0.42) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL14434449 | 0.90 | TRPM8 (0.43) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL14434501 | 0.89 | CXCR2 (0.48) | ALDH1A1MAPTPOLBHTTLMNA | |
| SCHEMBL14434454 | 0.89 | CXCR2 (0.41) | ALDH1A1MAPTMETAP2LMNAPABPC1 | |
| SCHEMBL5318868 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTMETAP2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |