Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434863 | 0.92 | PTPN5 (0.46) | KMT2AALDH1A1MAPTMEN1SERPINE1 | |
| SCHEMBL14434450 | 0.91 | CXCR2 (0.47) | KMT2AALDH1A1MAPTCXCR2MEN1 | |
| SCHEMBL14434456 | 0.90 | L3MBTL1 (0.44) | KMT2AALDH1A1MAPTCXCR2MEN1 | |
| SCHEMBL14434860 | 0.90 | ALDH1A1 (0.48) | KMT2AMCL1ALDH1A1MAPTCXCR2 | |
| SCHEMBL14434449 | 0.89 | TRPM8 (0.43) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14434873 | 0.89 | L3MBTL1 (0.43) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5342566 | 0.89 | POLB (0.47) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14434454 | 0.87 | CXCR2 (0.41) | KMT2AALDH1A1MAPTCXCR2MEN1 | |
| SCHEMBL14434499 | 0.86 | POLB (0.42) | KMT2AALDH1A1MAPTCXCR2MEN1 | |
| SCHEMBL14434501 | 0.85 | CXCR2 (0.48) | KMT2APTGDR2ALDH1A1MAPTCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |