Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851603 | 0.75 | NPC1 (0.42) | CA1CA2CA7CA12CA9 | |
| SCHEMBL28451650 | 0.74 | KMT2A (0.37) | CA1CA2CA7CA12CA9 | |
| SCHEMBL28898006 | 0.73 | KMT2A (0.36) | CA1CA2CA7CA12CA9 | |
| Lithium Ion SCHEMBL2890318 | 0.73 | CA1 (0.40) | CA1CA2CA7CA12CA9 | |
| SCHEMBL13870630 | 0.69 | KMT2A (0.39) | CA1CA2CA7CA12CA9 | |
| SCHEMBL31305335 | 0.67 | CA1 (0.50) | CA1CA2CA7CA12CA9 | |
| Lithium Ion SCHEMBL29875131 | 0.67 | CLTC (0.44) | CA1CA2CA7CA12CA9 | |
| SCHEMBL3678283 | 0.67 | SNCA (0.35) | CA1CA2CA9TTRMEN1 | |
| SCHEMBL9009874 | 0.66 | TTR (0.51) | CA1CA2CA9TTRMEN1 | |
| SCHEMBL3505111 | 0.62 | TTR (0.53) | TTRMEN1KMT2AAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208192-A1 | NUCLEIC ACID AMPLIFICATION EMPLOYING TEMPERATURE OSCILLATION | ENIGMA DIAGNOSTICS LIMITED (GB) | 2012-08-16 | — | — | US | disclosed |
| EP-2475783-A1 | NUCLEIC ACID AMPLIFICATION EMPLOYING TEMPERATURE OSCILLATION | Enigma Diagnostics Limited (GB) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011030145-A1 | NUCLEIC ACID AMPLIFICATION EMPLOYING TEMPERATURE OSCILLATION | ENIGMA DIAGNOSTICS LIMITED (GB) | 2011-03-17 | — | — | WO | disclosed |