Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451650 | 0.84 | KMT2A (0.37) | NPC1RAB9ACA1CA2CA12 | |
| SCHEMBL28898006 | 0.83 | KMT2A (0.36) | NPC1RAB9ACA1CA2CA12 | |
| SCHEMBL14502330 | 0.76 | NPC1 (0.61) | NPC1RAB9ACA1CA2CA12 | |
| SCHEMBL31305335 | 0.76 | CA1 (0.50) | NPC1RAB9ACA1CA2CA12 | |
| SCHEMBL13870630 | 0.75 | KMT2A (0.39) | NPC1RAB9ACA1CA2CA12 | |
| SCHEMBL1443489 | 0.75 | CA1 (0.40) | CA1CA2CA12CA9KMT2A | |
| Lithium Ion SCHEMBL95351 | 0.74 | CLTC (0.44) | CA1CA2CA12CA9KMT2A | |
| Lithium Ion SCHEMBL29875131 | 0.74 | CLTC (0.44) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL28312087 | 0.70 | KMT2A (0.34) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL27429842 | 0.69 | HEXA (0.43) | NPC1RAB9ACA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116430055-A | T cell immunological state marker combination for evaluating chronic pathological state of T lymphocyte of disease and application thereof | 中南大学湘雅二医院 | 2023-07-14 | — | — | CN | disclosed |
| CN-108359719-A | The detection method of gene imbalance | 奎斯特诊断投资公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-102459648-A | Method for detecting gene disorder | QUEST DIAGNOSTICS INVEST INC | 2012-05-16 | — | — | CN | disclosed |