Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451650 | 0.89 | KMT2A (0.37) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL28898006 | 0.88 | KMT2A (0.36) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| Lithium Ion SCHEMBL95351 | 0.79 | CLTC (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| Lithium Ion SCHEMBL29875131 | 0.79 | CLTC (0.44) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL27851603 | 0.75 | NPC1 (0.42) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL28312087 | 0.75 | KMT2A (0.34) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL31305335 | 0.72 | CA1 (0.50) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL5527165 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL1443489 | 0.69 | CA1 (0.40) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL14502330 | 0.69 | NPC1 (0.61) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090090628-A1 | NUCLEIC ACID DERIVATIVES AND METHODS OF USE | BIODYNAMICS LABORATORY, INC (JP) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090090628-A1 | NUCLEIC ACID DERIVATIVES AND METHODS OF USE | NSUN3, TRDMT1, NSUN2 | KMT2A 2066/4885MEN1 2655/4885USP2 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.