Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 2/20 | 0.45 |
| ▸ | CYBB | P04839 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KLK3 | P07288 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435011 | 1.00 | CHRNA7 (0.46) | CHRNA7MAPTGAAUSP7CYBB | |
| SCHEMBL14435013 | 0.86 | MAPT (0.49) | CHRNA7MAPTGAAUSP7AR | |
| SCHEMBL14435016 | 0.86 | MAPT (0.49) | CHRNA7MAPTGAAUSP7AR | |
| SCHEMBL14435015 | 0.86 | MAPT (0.49) | CHRNA7MAPTGAAUSP7AR | |
| SCHEMBL14435014 | 0.86 | MAPT (0.49) | CHRNA7MAPTGAAUSP7AR | |
| SCHEMBL5521706 | 0.79 | MAPT (0.54) | CHRNA7MAPTGAAUSP7CYBB | |
| SCHEMBL5522483 | 0.79 | MAPT (0.54) | CHRNA7MAPTGAAUSP7CYBB | |
| SCHEMBL5516230 | 0.76 | CHRNA7 (0.76) | CHRNA7MAPTGAAUSP7CYBB | |
| SCHEMBL5522476 | 0.76 | CHRNA7 (0.76) | CHRNA7MAPTGAAUSP7CYBB | |
| SCHEMBL5523607 | 0.76 | CHRNA7 (0.76) | CHRNA7MAPTGAAUSP7CYBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179172-A1 | Positive modulators of nicotinic acetylcholine receptors | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179172-A1 | Positive modulators of nicotinic acetylcholine receptors | CHRNA1, CHRNA2, CHRM1 | CHRNA7 10/4885MAPT 1307/4885GAA 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.