Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435511 | 0.85 | ALDH1A1 (0.49) | HRH3CYP2C9EPHX2 | |
| SCHEMBL14435508 | 0.82 | EPHX2 (0.48) | HRH3CYP2C9EPHX2DRD2HTR2A | |
| SCHEMBL5325795 | 0.79 | HTR2A (0.44) | HRH3CYP2C9EPHX2DRD2HTR2A | |
| SCHEMBL14435507 | 0.79 | EPHX2 (0.42) | HRH3CYP2C9EPHX2DRD2HTR2A | |
| SCHEMBL5322616 | 0.78 | RXRA (0.51) | CYP2C9EPHX2DRD2HTR2AHTR2C | |
| SCHEMBL14435119 | 0.78 | NPC1 (0.48) | CNR2HRH3CYP2C9EPHX2DRD2 | |
| SCHEMBL14435512 | 0.77 | HTR2A (0.48) | HRH3CYP2C9EPHX2DRD2HTR2A | |
| SCHEMBL14435510 | 0.72 | HTR2A (0.42) | HRH3CYP2C9EPHX2DRD2HTR2A | |
| SCHEMBL11918450 | 0.72 | HRH3 (0.60) | HRH3 | |
| SCHEMBL14435114 | 0.71 | HTR2A (0.43) | HRH3CYP2C9EPHX2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088462-A1 | SPIROCHROMANE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |