SCHEMBL14435149

SCHEMBL14435149

CCc1c(Cl)cc(O)cc1C(=O)C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.40
CNR1 P21554 1/20 0.40
DRD2 P14416 1/20 0.34
TSHR P16473 2/20 0.34
HPGD P15428 1/20 0.34
MGLL Q99685 1/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MELK Q14680 1/20 0.34
KDM2B Q8NHM5 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14435146 0.93 ALDH1A1 (0.36) DRD2TSHRHPGDMGLLTP53
SCHEMBL4122359 0.80 CNR2 (0.44) CNR2CNR1TSHRHPGDMGLL
SCHEMBL4132557 0.77 TAS1R3 (0.41) CNR2CNR1DRD2TSHRLMNA
SCHEMBL4121777 0.72 ALDH1A1 (0.41) TSHRHPGDMGLLMELK
SCHEMBL10937568 0.70 CYP3A4 (0.50) TSHRHPGDSMN1; SMN2LMNA
SCHEMBL4125864 0.69 TPMT (0.41) DRD2TSHRHPGDMGLLMELK
SCHEMBL13696934 0.69 NPC1 (0.43) CNR2CNR1TSHRHPGDTP53
SCHEMBL5989722 0.68 SMN1; SMN2 (0.46) MGLLSMN1; SMN2
SCHEMBL4122910 0.67 CA12 (0.50) CNR2CNR1TSHR
SCHEMBL11679259 0.66 HPGD (0.57) TSHRHPGDMGLLKDM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007090434-A1 SUBSTITUTED ARYL OXIMES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-08-16 WO disclosed