Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874672 | 1.00 | ADRB2 (0.52) | ADRB2AOC3TSHRMAPK1HIF1A | |
| SCHEMBL18762840 | 0.87 | CHRNA7 (0.43) | KDM4E | |
| SCHEMBL11230687 | 0.84 | TYR (0.42) | HIF1AHTTLMNAIDO1 | |
| SCHEMBL7035638 | 0.77 | ADRB2 (0.48) | ADRB2AOC3TSHRMAPK1HIF1A | |
| SCHEMBL12313 | 0.77 | CHRNA7 (0.61) | TSHRTDP1 | |
| SCHEMBL197810 | 0.75 | ADRB2 (0.65) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL8302666 | 0.75 | ALDH1A1 (0.55) | TSHRMAPK1HIF1ATDP1TP53 | |
| SCHEMBL853383 | 0.75 | TDP1 (0.44) | TSHRMAPK1HIF1ATDP1HTT | |
| SCHEMBL4592098 | 0.75 | PYCR1 (0.37) | — | |
| SCHEMBL2382760 | 0.75 | PYCR1 (0.60) | HIF1ALMNACYP2A6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096740-A2 | NOVEL CEPHALOSPORINS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-08-30 | — | — | WO | disclosed |