Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180103 | 0.89 | CCKAR (0.36) | CCKARALDH1A1CNR1CNR2 | |
| SCHEMBL3085850 | 0.88 | ALDH1A1 (0.35) | CCKARALDH1A1CNR1CNR2F10 | |
| SCHEMBL4928211 | 0.75 | CNR1 (0.41) | CCKARCNR1CNR2 | |
| SCHEMBL3094082 | 0.75 | CNR2 (0.43) | CNR1CNR2F10 | |
| SCHEMBL13145271 | 0.74 | CNR1 (0.38) | CCKARALDH1A1CNR1CNR2F10 | |
| SCHEMBL3086840 | 0.74 | CNR1 (0.38) | CCKARALDH1A1CNR1CNR2F10 | |
| SCHEMBL3088156 | 0.73 | CNR1 (0.37) | CCKARALDH1A1CNR1CNR2 | |
| SCHEMBL3085780 | 0.73 | CNR1 (0.37) | CCKARALDH1A1CNR1CNR2 | |
| SCHEMBL3090627 | 0.71 | FAAH (0.37) | ALDH1A1CNR1CNR2F10 | |
| SCHEMBL3088729 | 0.71 | FAAH (0.37) | ALDH1A1CNR1CNR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095513-A1 | TETRAHYDR0-2H-INDAZ0LE DERIVATIVES FOR USE AS CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, NV (BE) | 2007-08-23 | — | — | WO | disclosed |