Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088156 | 1.00 | CNR1 (0.37) | CNR1CNR2FAAHCFTRCCKAR | |
| SCHEMBL3090627 | 0.91 | FAAH (0.37) | CNR1CNR2FAAHMAPTTP53 | |
| SCHEMBL3088729 | 0.91 | FAAH (0.37) | CNR1CNR2FAAHMAPTTP53 | |
| SCHEMBL3086840 | 0.90 | CNR1 (0.38) | CNR1CNR2FAAHCFTRCCKAR | |
| SCHEMBL13145271 | 0.90 | CNR1 (0.38) | CNR1CNR2FAAHCFTRCCKAR | |
| SCHEMBL4928211 | 0.84 | CNR1 (0.41) | CNR1CNR2CFTRCCKARMAPT | |
| SCHEMBL3094082 | 0.77 | CNR2 (0.43) | CNR1CNR2 | |
| SCHEMBL13180103 | 0.76 | CCKAR (0.36) | CNR1CNR2CCKARALDH1A1 | |
| SCHEMBL3085850 | 0.74 | ALDH1A1 (0.35) | CNR1CNR2CCKARMAPTALDH1A1 | |
| SCHEMBL14435695 | 0.73 | CCKAR (0.33) | CNR1CNR2CCKARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | disclosed |