Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435695 | 0.88 | CCKAR (0.33) | ALDH1A1CCKARCNR1CNR2F10 | |
| SCHEMBL13180103 | 0.85 | CCKAR (0.36) | ALDH1A1CCKARCNR1CNR2 | |
| SCHEMBL4928211 | 0.76 | CNR1 (0.41) | CCKARMAPTCNR1CNR2 | |
| SCHEMBL3086840 | 0.75 | CNR1 (0.38) | ALDH1A1CCKARMAPTCNR1CNR2 | |
| SCHEMBL13145271 | 0.75 | CNR1 (0.38) | ALDH1A1CCKARMAPTCNR1CNR2 | |
| SCHEMBL3094082 | 0.74 | CNR2 (0.43) | CNR1CNR2F10 | |
| SCHEMBL3088156 | 0.74 | CNR1 (0.37) | ALDH1A1CCKARMAPTCNR1CNR2 | |
| SCHEMBL3085780 | 0.74 | CNR1 (0.37) | ALDH1A1CCKARMAPTCNR1CNR2 | |
| SCHEMBL3088729 | 0.72 | FAAH (0.37) | ALDH1A1MAPTCNR1CNR2F10 | |
| SCHEMBL3090627 | 0.72 | FAAH (0.37) | ALDH1A1MAPTCNR1CNR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | claimed |
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | disclosed |
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, GPR35 | ALDH1A1 1794/4885CCKAR 64/4885MAPT 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.