SCHEMBL1443592

SCHEMBL1443592

CC(S)C(=O)OC(=O)CN

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PTGS2 P35354 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579105 0.98
SCHEMBL7707533 0.81 NAAA (0.37) LMNAALDH1A1MAPTPTGS2TDP1
SCHEMBL9420755 0.79 TSHR (0.44) LMNAALDH1A1MAPTPTGS2TDP1
SCHEMBL3253032 0.79 TP53 (0.33) LMNAMAPTKDM4ECYP1A2
SCHEMBL1537296 0.79 GRIN2D (0.33) LMNAKDM4ECYP1A2
SCHEMBL186138 0.79 GRIN2D (0.33) LMNAKDM4ECYP1A2
SCHEMBL8837532 0.78 ENPEP (0.35)
SCHEMBL4215424 0.77 TP53 (0.32) LMNAKDM4ECYP1A2
SCHEMBL3975721 0.77 TP53 (0.32) LMNAKDM4ECYP1A2
SCHEMBL4215465 0.77 TP53 (0.32) LMNAKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105997878-A Composite micelle carrier medicine composition for reducing free radical damage 原创生医股份有限公司 2016-10-12 CN claimed
US-9226967-B2 Chelating complex micelles drug carrier Original BioMedicals Co., Ltd (TW) 2016-01-05 US claimed
US-9220786-B2 Pharmaceutical composition of chelating complex micelles Original BioMedicals Co., Ltd (TW) 2015-12-29 US claimed
US-9211341-B2 Method of manufacturing a pharmaceutical composition having chelating type complex micelles ORIGINAL BIOMEDICALS CO., LTD. (TW) 2015-12-15 US claimed
CN-104114188-A Composite micelle carrier medicine composition for reducing free radical damage ORIGINAL BIOMEDICALS CO LTD 2014-10-22 CN claimed
US-20140303329-A1 Method of manufacturing a pharmaceutical composition having chelating type complex micelles Original BioMedicals Co., Ltd (TW) 2014-10-09 US claimed
US-20140296435-A1 PHARMACEUTICAL COMPOSITION OF CHELATING COMPLEX MICELLES Original BioMedicals Co., Ltd (TW) 2014-10-02 US claimed
US-20140296451-A1 CHELATING COMPLEX MICELLES DRUG CARRIER Original BioMedicals Co., Ltd (TW) 2014-10-02 US claimed
EP-2783679-A1 DRUG CARRIER WITH CHELATING COMPOSITE MICELL AND USE THEREOF Original BioMedicals Co., Ltd. (TW) 2014-10-01 EP claimed
US-20130131283-A1 Drug Carrier with Chelating Complex Micelles and the Application thereof Original Biomedicals, Co., Ltd. (TW) 2013-05-23 US claimed
WO-2011031284-A1 POLYMERIC CARRIER COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2011-03-17 WO claimed
US-20100069293-A1 POLYMERIC CARRIER COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2010-03-18 US claimed
EP-2026824-A2 MULTIFUNCTIONAL BLOOD SUBSTITUTE The United States Of America As Represented By the Sectretary of the Navy (US) 2009-02-25 EP claimed
WO-2007136555-A2 MULTIFUNCTIONAL BLOOD SUBSTITUTE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2007-11-29 WO claimed
US-20070265195-A1 Multifunctional blood substitute FREILICH DANIEL A 2007-11-15 US claimed
EP-2783679-B1 DRUG CARRIER WITH CHELATING COMPOSITE MICELLE AND USE THEREOF ORIGINAL BIOMEDICALS CO LTD (TW) 2018-07-18 EP disclosed
US-9795677-B2 Method for reducing damage caused by free radicals Original BioMedicals Co., Ltd (TW) 2017-10-24 US disclosed
EP-0202081-A2 A single step heterogeneous assay and kit SYNTEX (U.S.A.) INC. (US) 1986-11-20 EP disclosed
US-4356118-A Tryptophan derivatives G. D. SEARLE & CO. (US) 1982-10-26 US disclosed
EP-0013261-A1 Guaiacol esters of alpha- and beta-mercaptopropionylalanine and alpha- and beta-mercaptopropionylglycine, process for their preparation and pharmaceutical compositions containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1980-07-09 EP disclosed