SCHEMBL8837532

SCHEMBL8837532

CC(CS)C(=O)OC(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.35
CPB2 Q96IY4 1/20 0.33
GABRR1 P24046 2/20 0.31
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704471 0.83 ALDH1A1 (0.35) ENPEPTSHRHSD17B10
SCHEMBL7704470 0.82 ENPEP (0.38) ENPEP
SCHEMBL1252195 0.81 CYP1A2 (0.33) GABRR1
SCHEMBL28178891 0.79 CYP1A2 (0.50) ENPEPGABRR1TSHR
SCHEMBL1443592 0.78 LMNA (0.30)
SCHEMBL28048632 0.78 LMNA (0.32) GABRR1TSHR
SCHEMBL9579105 0.77
SCHEMBL361160 0.77 PTGS1 (0.44) ENPEPCPB2
SCHEMBL5149928 0.77 PTGS1 (0.44) ENPEPCPB2
SCHEMBL186138 0.76 GRIN2D (0.33) GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5690904-A BRAIN IMAGING AGENTS AMERSHAM INTERNATIONAL PLC (GB) 1997-11-25 US disclosed