Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 7/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14436006 | 1.00 | ADAM17 (0.43) | ADAM17ADAMTS5CCR1PROKR1MEN1 | |
| SCHEMBL14436010 | 0.90 | ADAM17 (0.41) | ADAM17ADAMTS5CCR1PROKR1MEN1 | |
| SCHEMBL14435596 | 0.90 | AKT1 (0.43) | ADAM17ADAMTS5AKT1 | |
| SCHEMBL14435997 | 0.88 | CCR1 (0.43) | ADAM17ADAMTS5CCR1ALDH1A1CYP51A1 | |
| SCHEMBL14436003 | 0.88 | CCR1 (0.43) | ADAM17ADAMTS5CCR1ALDH1A1CYP51A1 | |
| SCHEMBL12713182 | 0.84 | CALCA (0.46) | CCR1ALDH1A1CYP51A1 | |
| SCHEMBL14435996 | 0.84 | ADAM17 (0.43) | ADAM17ADAMTS5CCR1PROKR1MEN1 | |
| SCHEMBL14436009 | 0.84 | ADAM17 (0.43) | ADAM17ADAMTS5CCR1PROKR1MEN1 | |
| SCHEMBL14435628 | 0.83 | KMT2A (0.46) | CCR1KMT2AALDH1A1CYP51A1 | |
| SCHEMBL14435995 | 0.81 | ADAM17 (0.41) | ADAM17ADAMTS5CCR1PROKR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |