Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 13/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057971 | 0.87 | AR (0.47) | ARSLC22A12EPAS1VEGFAPOLB | |
| SCHEMBL19057972 | 0.81 | AR (0.42) | ARSLC22A12POLBGAAPLA2G7 | |
| SCHEMBL14435933 | 0.80 | PLA2G7 (0.53) | ARSLC22A12PLA2G7 | |
| SCHEMBL19057964 | 0.79 | AR (0.41) | ARSLC22A12EPAS1PLA2G7 | |
| SCHEMBL5949965 | 0.77 | AR (0.56) | ARSLC22A12EPAS1POLBGAA | |
| SCHEMBL15994257 | 0.76 | AR (0.47) | ARSLC22A12EPAS1PLA2G7 | |
| SCHEMBL17407526 | 0.76 | AR (0.50) | ARSLC22A12EPAS1 | |
| SCHEMBL4103326 | 0.76 | HTR2A (0.53) | ARSLC22A12POLBGAA | |
| SCHEMBL14437176 | 0.76 | PLA2G7 (0.41) | ARSLC22A12PLA2G7 | |
| SCHEMBL5837296 | 0.74 | SLC22A12 (0.57) | ARSLC22A12PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089646-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-08-09 | — | — | WO | disclosed |