Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 13/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14437176 | 0.85 | PLA2G7 (0.41) | PLA2G7HPGDTP53HSD17B10AR | |
| SCHEMBL19057972 | 0.83 | AR (0.42) | PLA2G7ARSLC22A12 | |
| SCHEMBL19057964 | 0.82 | AR (0.41) | PLA2G7ARSLC22A12 | |
| SCHEMBL14437173 | 0.80 | AR (0.52) | PLA2G7ARSLC22A12 | |
| SCHEMBL19057971 | 0.78 | AR (0.47) | PLA2G7ARSLC22A12 | |
| SCHEMBL24022846 | 0.75 | MOK (0.47) | PLA2G7SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL7123049 | 0.74 | PLA2G7 (0.51) | PLA2G7HPGDTP53NPSR1HSD17B10 | |
| SCHEMBL17407526 | 0.73 | AR (0.50) | ARSLC22A12 | |
| SCHEMBL2527810 | 0.73 | ALDH1A1 (0.48) | PLA2G7LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5949965 | 0.71 | AR (0.56) | PLA2G7ARSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089646-A1 | KINASE INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-08-09 | — | — | WO | disclosed |