Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057964 | 0.87 | AR (0.41) | ARSLC22A12PLA2G7 | |
| SCHEMBL14437176 | 0.86 | PLA2G7 (0.41) | ARSLC22A12PLA2G7 | |
| SCHEMBL14435933 | 0.83 | PLA2G7 (0.53) | ARSLC22A12PLA2G7 | |
| SCHEMBL14437173 | 0.81 | AR (0.52) | ARSLC22A12PLA2G7POLBGAA | |
| SCHEMBL19057971 | 0.79 | AR (0.47) | ARSLC22A12PLA2G7KCNH2POLB | |
| SCHEMBL5949965 | 0.72 | AR (0.56) | ARSLC22A12PLA2G7POLBGAA | |
| SCHEMBL17407526 | 0.72 | AR (0.50) | ARSLC22A12HTR2ASLC6A4KCNH2 | |
| SCHEMBL15994257 | 0.69 | AR (0.47) | ARSLC22A12PLA2G7KCNH2 | |
| SCHEMBL4103326 | 0.69 | HTR2A (0.53) | ARSLC22A12HTR2ASLC6A4POLB | |
| SCHEMBL13924849 | 0.68 | SLC6A4 (0.46) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961744-B1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC (US) | 2017-06-28 | — | — | EP | disclosed |