Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 16/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057972 | 0.87 | AR (0.42) | ARPLA2G7SLC22A12 | |
| SCHEMBL14437176 | 0.84 | PLA2G7 (0.41) | ARPLA2G7SLC22A12 | |
| SCHEMBL14435933 | 0.82 | PLA2G7 (0.53) | ARPLA2G7SLC22A12 | |
| SCHEMBL16004751 | 0.82 | HTR2A (0.37) | — | |
| SCHEMBL14436458 | 0.82 | SLC6A4 (0.38) | — | |
| SCHEMBL14437173 | 0.79 | AR (0.52) | ARPLA2G7SLC22A12EPAS1 | |
| SCHEMBL19057971 | 0.77 | AR (0.47) | ARPLA2G7SLC22A12CYP2C8CYP2C9 | |
| SCHEMBL15994534 | 0.74 | AR (0.39) | ARPLA2G7SLC22A12CYP2C8CYP2C9 | |
| SCHEMBL15994535 | 0.74 | AR (0.39) | ARPLA2G7SLC22A12CYP2C8CYP2C9 | |
| SCHEMBL17407528 | 0.70 | NTRK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961744-B1 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | ARRAY BIOPHARMA INC (US) | 2017-06-28 | — | — | EP | disclosed |