SCHEMBL144390

SCHEMBL144390

C=C(CC)C(=O)NC(OC)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.34
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10876493 0.84 TGFBR1 (0.33) TGFBR1
SCHEMBL36513 0.79 TGFBR1 (0.50) TGFBR1
SCHEMBL2532099 0.75 TGFBR1 (0.37) TGFBR1
SCHEMBL7160038 0.72 CA1 (0.32)
SCHEMBL8643965 0.71 TSHR (0.39) TGFBR1
SCHEMBL10381604 0.69 KDM4E (0.41) TGFBR1
SCHEMBL20861009 0.68 MMP1 (0.45)
SCHEMBL238196 0.67 SLC1A3 (0.38) TGFBR1
SCHEMBL28923240 0.67
SCHEMBL9515219 0.67 TGFBR1 (0.50) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120108678-A1 BRANCHED COPOLYMERS, COMPOSITIONS AND USES UNILEVER PLC (GB) 2012-05-03 US claimed
US-9414997-B2 Benefit delivery particle, compositions comprising said particles and a method for treating substrates CONOPCO, INC. (US) 2016-08-16 US disclosed
WO-2015189624-A2 FUNCTIONALISED MATERIAL IMPERIAL INNOVATIONS LIMITED (GB) 2015-12-17 WO disclosed
WO-2015189625-A1 MATERIAL FUNCTIONALISED WITH A POLYMER IMPERIAL INNOVATIONS LIMITED (GB) 2015-12-17 WO disclosed
US-20150272839-A1 BENEFIT DELIVERY PARTICLE, COMPOSITIONS COMPRISING SAID PARTICLES AND A METHOD FOR TREATING SUBSTRATES CONOPCO, INC. D/B/A UNILEVER (US) 2015-10-01 US disclosed
US-20130345358-A1 USE OF BRANCHED ADDITION COPOLYMERS IN CURING SYSTEMS UNILEVER PLC (GB) 2013-12-26 US disclosed
US-20120178835-A1 USE OF BRANCHED ADDITION COPLYMERS IN FILMS AND MEMBRANES UNILEVER PLC (GB) 2012-07-12 US disclosed
US-20120108678-A1 BRANCHED COPOLYMERS, COMPOSITIONS AND USES UNILEVER PLC (GB) 2012-05-03 US disclosed
US-20120095111-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US disclosed
US-20120095112-A1 BRANCHED POLYMER DISPERSANTS UNILEVER HOUSE (GB) 2012-04-19 US disclosed
US-20120095110-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US disclosed
US-20120059069-A1 AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, AND USES UNILEVER PLC (GB) 2012-03-08 US disclosed
EP-2102256-B1 POLYMERS UNILEVER PLC (GB) 2012-01-25 EP disclosed
US-20110172314-A1 AMPHIPHILIC BRANCHED POLYMERS AND THEIR USE AS EMULSIFIERS UNILEVER N.V. (NL) 2011-07-14 US disclosed
WO-2011033261-A1 USE OF BRANCHED ADDITION COPOLYMERS IN FILMS AND MEMBRANES UNILEVER PLC (GB) 2011-03-24 WO disclosed
WO-2011033262-A1 USE OF BRANCHED ADDITION COPOLYMERS IN CURING SYSTEMS UNILEVER PLC (GB) 2011-03-24 WO disclosed
WO-2011029579-A2 USE OF POLYMERS UNILEVER PLC (GB) 2011-03-17 WO disclosed
EP-2285848-A1 AMPHIPHILIC BRANCHED POLYMERS AND THEIR USE AS EMULSIFIERS Unilever N.V. (NL) 2011-02-23 EP disclosed
US-20100130641-A1 Polymers UNILEVER PLC (GB) 2010-05-27 US disclosed
WO-2009144471-A1 AMPHIPHILIC BRANCHED POLYMERS AND THEIR USE AS EMULSIFIERS UNILEVER N.V. (NL) 2009-12-03 WO disclosed