SCHEMBL2532099

SCHEMBL2532099

C=C(CC)C(=O)NC(O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.37
TET2 Q6N021 3/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
FFAR3 O14843 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8946782 0.81 PLA2G2A (0.38) TGFBR1
SCHEMBL7160038 0.80 CA1 (0.32)
SCHEMBL7212042 0.76 TET2 (0.32) TGFBR1TET2TET3TET1
SCHEMBL8643965 0.76 TSHR (0.39) TGFBR1
SCHEMBL472271 0.76 TGFBR1 (0.55) TGFBR1
SCHEMBL144390 0.75 TGFBR1 (0.34) TGFBR1
SCHEMBL10876493 0.73 TGFBR1 (0.33) TGFBR1
SCHEMBL20861009 0.72 MMP1 (0.45)
SCHEMBL11025654 0.71 TGFBR1 (0.32) TGFBR1
SCHEMBL11024525 0.71 ALDH1A1 (0.35) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2370449-A1 SILSESQUIOXANE PHOTOINITIATORS BASF SE (DE) 2011-10-05 EP disclosed
WO-2010063612-A1 SILSESQUIOXANE PHOTOINITIATORS BASF SE (DE) 2010-06-10 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed