Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439367 | 0.86 | KDM4E (0.41) | CTSSMEN1KMT2A | |
| SCHEMBL14399315 | 0.86 | CTSS (0.48) | CTSSCAPN1CTSBCTSKCTSH | |
| SCHEMBL13624749 | 0.86 | CTSS (0.48) | CTSSCAPN1CTSBCTSKCTSH | |
| SCHEMBL15744682 | 0.81 | MMP3 (0.40) | CTSSCTSBCTSKCTSHCTSC | |
| SCHEMBL26403817 | 0.81 | MMP3 (0.42) | — | |
| SCHEMBL2623712 | 0.78 | APLNR (0.40) | CTSSCAPN1CTSBCTSKCTSH | |
| SCHEMBL13624745 | 0.75 | PSMB5 (0.38) | CTSSCTSBCTSKCTSHCTSC | |
| SCHEMBL15745544 | 0.75 | CRHR1 (0.37) | — | |
| SCHEMBL15744687 | 0.73 | APLNR (0.40) | CTSSCAPN1 | |
| SCHEMBL26403878 | 0.73 | GRPR (0.43) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |