Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967638 | 0.89 | TDP1 (0.39) | MEN1KMT2ATP53MAPTRECQL | |
| SCHEMBL6974497 | 0.86 | MEN1 (0.34) | MEN1KMT2AMAPTEPHX1HTT | |
| SCHEMBL6974427 | 0.86 | MAPT (0.38) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL14439837 | 0.85 | — | — | |
| SCHEMBL6962940 | 0.85 | HSP90B1 (0.31) | MEN1KMT2ASMN1; SMN2CYP1A2LMNA | |
| SCHEMBL14001817 | 0.85 | TP53 (0.36) | MEN1KMT2ATP53MAPTRECQL | |
| SCHEMBL7081608 | 0.85 | LMNA (0.36) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL6966022 | 0.85 | ADRA1D (0.36) | MEN1KMT2ATP53MAPTGRM5 | |
| SCHEMBL6962070 | 0.84 | MEN1 (0.30) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14439861 | 0.84 | TP53 (0.36) | MEN1KMT2ATP53MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |