Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962314 | 0.92 | L3MBTL1 (0.36) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL14001658 | 0.90 | P2RX3 (0.35) | MAPTTBXA2RTDP1TP53 | |
| SCHEMBL13996465 | 0.89 | P2RX3 (0.41) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL6972846 | 0.89 | P2RX3 (0.34) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6967638 | 0.88 | TDP1 (0.39) | L3MBTL1LMNAMEN1KMT2AALDH1A1 | |
| Capravirine SCHEMBL40347 | 0.87 | PIM1 (0.35) | L3MBTL1SMN1; SMN2KDM4ELMNAMEN1 | |
| Capravirine SCHEMBL4656686 | 0.87 | PIM1 (0.35) | L3MBTL1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL6961345 | 0.87 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL14439871 | 0.87 | P2RX3 (0.33) | LMNAHTTMAPT | |
| SCHEMBL6969108 | 0.85 | TSHR (0.38) | L3MBTL1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |