Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434226 | 0.95 | REN (0.56) | RENACEPRCPACE2ALDH1A1 | |
| SCHEMBL8451995 | 0.95 | REN (0.56) | RENACEPRCPACE2ALDH1A1 | |
| SCHEMBL13533687 | 0.87 | PRCP (0.63) | RENACEPRCPACE2CMA1 | |
| SCHEMBL14440148 | 0.87 | REN (0.52) | RENACEACE2ALDH1A1CMA1 | |
| SCHEMBL8257154 | 0.87 | REN (0.52) | RENACEACE2CMA1CTRB1 | |
| SCHEMBL8256761 | 0.84 | ACE (0.69) | RENACEACE2TSHR | |
| SCHEMBL7337615 | 0.84 | ITGB3 (0.58) | RENACEPRCPCMA1MAPT | |
| SCHEMBL7402728 | 0.84 | ACE (0.55) | RENACEPRCPACE2CTRB1 | |
| SCHEMBL7402735 | 0.84 | ACE (0.55) | RENACEPRCPACE2CTRB1 | |
| SCHEMBL8265581 | 0.83 | REN (0.59) | RENACEACE2ALDH1A1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185060-A1 | Boronic acid thrombin inhibitors | TRIGEN LIMITED (GB) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185060-A1 | Boronic acid thrombin inhibitors | F2, ECE1, BCAT1 | REN 1635/4885ACE 230/4885PRCP 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.