Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208939 | 0.93 | MAPT (0.62) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL28373439 | 0.87 | MAPT (0.74) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL9205145 | 0.85 | KMT2A (0.62) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL1520013 | 0.84 | MAPT (0.70) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL28373441 | 0.83 | MAPT (0.60) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL16071264 | 0.81 | MAPT (1.00) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL9203635 | 0.80 | MAPT (0.64) | MAPTHPGDKMT2AMEN1KDM4E | |
| SCHEMBL14441242 | 0.80 | RAB9A (0.62) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL14441255 | 0.80 | PTGS1 (0.59) | MAPTHPGDKMT2AMEN1LMNA | |
| SCHEMBL3431608 | 0.78 | MAPT (0.84) | MAPTHPGDKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191378-A1 | Anthranilic acid derivatives and their use as activators of the hm74a receptor | ANTXR2, HCAR1, GPR88 | MAPT 4869/4885HPGD 651/4885KMT2A 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.