Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14318504 | 0.83 | CA12 (0.59) | ALDH1A1CXCR1CXCR2 | |
| SCHEMBL14318502 | 0.82 | CYP19A1 (0.47) | KMT2AALDH1A1CXCR1CXCR2KDM4E | |
| SCHEMBL12522061 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL552190 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL25018210 | 0.79 | ADRB2 (0.52) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL14852 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL3605081 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL4491485 | 0.78 | KMT2A (0.61) | KMT2AKDM4EPOLBTSHRRECQL | |
| SCHEMBL5606910 | 0.76 | KMT2A (0.59) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL5307276 | 0.76 | KMT2A (0.59) | KMT2AALDH1A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133128-B2 | Pyrazole derivatives as cannabinoid receptor 1 antagonists | RESEARCH TRIANGLE INSTITUTE (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140107157-A1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR 1 ANTAGONISTS | RESEARCH TRIANGLE INSTITUTE (US) | 2014-04-17 | — | — | US | disclosed |
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | CNR1, CNR2, GPR119 | KMT2A 2078/4885ALDH1A1 1216/4885CXCR1 1898/4885 |
| US-20140107157-A1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR 1 ANTAGONISTS | CNR1, CNR2, GPR119 | KMT2A 4409/4885ALDH1A1 2024/4885CXCR1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.