Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899770 | 0.87 | ADRB2 (0.50) | ADRB2ADRB1ADRB3KMT2AGHSR | |
| SCHEMBL18660179 | 0.80 | MEN1 (0.50) | KMT2AKDM4EPOLBRECQLALDH1A1 | |
| SCHEMBL14443028 | 0.79 | KMT2A (0.56) | ADRB3KMT2AKDM4EPOLBTSHR | |
| SCHEMBL146034 | 0.75 | IDO1 (0.45) | TSHRALDH1A1CA2CA1CA9 | |
| SCHEMBL8750065 | 0.75 | KMT2A (0.56) | KMT2AKDM4EPOLBTSHRRECQL | |
| SCHEMBL12522061 | 0.75 | KMT2A (0.56) | ADRB2ADRB1ADRB3KMT2AKDM4E | |
| SCHEMBL8897049 | 0.75 | ADRB2 (0.48) | ADRB2ADRB1ADRB3KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4348562 | 0.74 | KMT2A (0.54) | KMT2AKDM4EPOLBTSHRRECQL | |
| SCHEMBL5308930 | 0.73 | MEN1 (0.53) | KMT2ATSHRALDH1A1CA2CA1 | |
| SCHEMBL5384653 | 0.73 | KMT2A (0.54) | ADRB2ADRB1ADRB3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578101-B2 | Proteasome inhibitors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578101-B2 | Proteasome inhibitors | PSMG3, PSME1, PSMB1 | ADRB2 4256/4885ADRB1 3617/4885ADRB3 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.