Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605081 | 0.83 | KMT2A (0.61) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL4491485 | 0.83 | KMT2A (0.61) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL2100494 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL6338974 | 0.81 | KMT2A (0.70) | KMT2AMEN1RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL552189 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL7230378 | 0.81 | KMT2A (0.65) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL5314524 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL3599158 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL22497546 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 | |
| SCHEMBL14862123 | 0.81 | KMT2A (0.59) | KMT2AMEN1RECQLCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11932613-B2 | Process for preparing 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide | ADAMA AGAN LTD. (IL) | 2024-03-19 | — | — | US | disclosed |
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
| CN-108430981-B | Process for preparing 1,1, 3-trioxo-1, 2-benzothiazole-6-carboxamides | 阿达玛阿甘股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-108473450-B | Process for preparing 1,1, 3-trioxo-1, 2-benzothiazole-6-carboxamides | 阿达玛阿甘股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-113089005-B | Electrochemical synthesis method of sulfamide | 华南理工大学 | 2022-02-15 | — | — | CN | disclosed |
| US-20210347746-A1 | PROCESS FOR PREPARING 1,1,3-TRIOXO-1,2-BENZOTHIAZOLE-6-CARBOXAMIDE | ADAMA AGAN LTD. (IL) | 2021-11-11 | — | — | US | disclosed |
| WO-2021225407-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE INHIBITORY ACTIVITY, AND USE THEREOF | 주식회사 티씨노바이오사이언스 (KR) | 2021-11-11 | — | — | WO | disclosed |
| CN-113089005-A | Electrochemical synthesis method of sulfamide | 华南理工大学 | 2021-07-09 | — | — | CN | disclosed |
| EP-3397621-B1 | PROCESS FOR PREPARING 1,1,3-TRIOXO-1,2-BENZOTHIAZOLE-6-CARBOXAMIDE | ADAMA AGAN LTD (IL) | 2020-12-09 | — | — | EP | disclosed |
| EP-3397620-B1 | PROCESS FOR PREPARING 1.1.3-TRIOXO-1.2-BENZOTHIAZOLE-6-CARBOXAMIDE | ADAMA AGAN LTD (IL) | 2020-11-25 | — | — | EP | disclosed |
| US-20080113985-A1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED | 2008-05-15 | — | — | US | disclosed |
| US-20080081809-A1 | Novel Compounds | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-04-03 | — | — | US | disclosed |
| US-20080081809-A1 | Novel Compounds | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-04-03 | — | — | US | disclosed |
| WO-2008023161-A1 | 2-METHYLMORPHOLINE PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-20 | — | — | US | disclosed |
| US-7271270-B2 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070213323-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | Janssen Pharmaceuticals, Inc. | 2007-09-13 | — | — | US | disclosed |
| US-20070213323-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | Janssen Pharmaceuticals, Inc. | 2007-09-13 | — | — | US | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347746-A1 | PROCESS FOR PREPARING 1,1,3-TRIOXO-1,2-BENZOTHIAZOLE-6-CARBOXAMIDE | TMT1A, TST, CPS1 | KMT2A 1010/4885MEN1 3348/4885RECQL 3427/4885 |
| US-20070213323-A1 | NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS | GRM2, GRM1, GRM3 | KMT2A 1937/4885MEN1 3509/4885RECQL 962/4885 |
| US-11932613-B2 | Process for preparing 1,1,3-trioxo-1,2-benzothiazole-6-carboxamide | TMT1A, TST, CPS1 | KMT2A 1132/4885MEN1 3249/4885RECQL 3321/4885 |
| US-20080113985-A1 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | KMT2A 4241/4885MEN1 4705/4885RECQL 386/4885 |
| US-20070219228-A1 | Aryl substituted imidazonaphthyridines | IL2, IRF3, EIF2AK2 | KMT2A 3772/4885MEN1 4622/4885RECQL 3346/4885 |
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | ENPP1, ENPP3, PPA1 | KMT2A 3621/4885MEN1 644/4885RECQL 2259/4885 |
| US-20080081809-A1 | Novel Compounds | SLC10A1, ABCB11, PKD1 | KMT2A 3079/4885MEN1 64/4885RECQL 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.