Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 3/20 | 0.67 |
| ▸ | PARP1 known ✓ | P09874 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL27350158 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL27839064 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL27444367 | 1.00 | ALDH1A1 (0.93) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL1074283 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28180817 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30537001 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL28491203 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL30536983 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL6061130 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM | |
| Benzophenone SCHEMBL17745 | 0.97 | ALDH1A1 (1.00) | ALDH1A1SRD5A2TDP1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| CN-104371044-B | The preparation of a kind of metal ruthenium catalyst and the application in ring opening metathesis polymerization thereof | 上海克琴化工科技有限公司 | 2016-09-21 | — | — | CN | claimed |
| EP-2366752-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND USE OF SAME | MERCK PATENT GMBH (DE) | 2016-07-20 | — | — | EP | claimed |
| CN-104371044-A | Preparation of ruthenium metal catalyst and application of ruthenium metal catalyst in ring-opening metathesis polymerization | SHANGHAI COACHCHEM TECHNOLOGY CO LTD | 2015-02-25 | — | — | CN | claimed |
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | claimed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | claimed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | claimed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | claimed |
| CN-1894357-A | Novel materials for electroluminescence, and use thereof | MERCK PATENT GMBH (DE) | 2007-01-10 | — | — | CN | claimed |
| CN-117801747-A | Multi-order epoxy resin, preparation method and rapid detection method of curing degree of multi-order epoxy resin | 中路交科科技股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2021060275-A1 | ANTIREFLECTION STRUCTURE, SUBSTRATE WITH ANTIREFLECTION STRUCTURE, CAMERA MODULE, AND INFORMATION TERMINAL DEVICE | デクセリアルズ株式会社 | 2021-04-01 | — | — | WO | disclosed |
| WO-2020217793-A1 | ADHESIVE TAPE | 積水化学工業株式会社 | 2020-10-29 | — | — | WO | disclosed |
| CN-104371044-B | The preparation of a kind of metal ruthenium catalyst and the application in ring opening metathesis polymerization thereof | 上海克琴化工科技有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-104371044-A | Preparation of ruthenium metal catalyst and application of ruthenium metal catalyst in ring-opening metathesis polymerization | SHANGHAI COACHCHEM TECHNOLOGY CO LTD | 2015-02-25 | — | — | CN | disclosed |
| US-4229564-A | SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS | RAYCHEM CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4111908-A | POLYKETONES AND METHODS THEREFOR | RAYCHEM CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4024314-A | Electrical conductor insulated by a polyketones | RAYCHEM CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3965146-A | POLYMER INTERMEDIATE | RAYCHEM CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
| US-3956240-A | DIELECTRICS | RAYCHEM CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3953400-A | Polyketones and methods therefor | RAYCHEM CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |