Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445367 | 0.92 | MAPK1 (0.38) | MAPK1ALDH1A1KDM4EMAPTPTGER4 | |
| SCHEMBL14445361 | 0.81 | ALDH1A1 (0.38) | MAPK1HCAR3ALDH1A1KDM4EMAPT | |
| SCHEMBL14445353 | 0.81 | ALDH1A1 (0.36) | MAPK1CNR1CNR2MAOAMAOB | |
| SCHEMBL14445298 | 0.81 | CNR1 (0.33) | CNR1CNR2ALDH1A1 | |
| SCHEMBL14445360 | 0.81 | CNR1 (0.34) | MAPK1CNR1CNR2MAOAMAOB | |
| SCHEMBL14445237 | 0.81 | KMO (0.35) | MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5427295 | 0.80 | LRRK2 (0.37) | MAOAMAOBALDH1A1KDM4EMAPT | |
| SCHEMBL14445269 | 0.80 | KMO (0.40) | ALDH1A1KDM4EMAPTLMNATDP1 | |
| SCHEMBL14445310 | 0.79 | JAK2 (0.33) | KDM4EKDM4C | |
| SCHEMBL14445365 | 0.79 | LMNA (0.31) | MAOAMAOBALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |