Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218966 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL12189513 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL27676339 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL17493449 | 0.79 | ALDH1A1 (0.57) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL15382510 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL276310 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL19426682 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL19557956 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL63945 | 0.78 | ALDH1A1 (0.67) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA | |
| SCHEMBL86088 | 0.78 | ALDH1A1 (0.67) | ALDH1A1CYP2C19CYP3A4CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230257353-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | US | disclosed |
| WO-2023014907-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| US-10640510-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190135815-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-05-09 | — | — | US | disclosed |
| EP-0790255-B1 | Monoclonal antibodies directed to the cytotoxic lymphocyte maturation factor | HOFFMANN LA ROCHE (CH) | 2007-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257353-A1 | IONIZABLE LIPIDOIDS AND THEIR USES | TTR, PYGL, FABP1 | ALDH1A1 2035/4885CYP2C19 1005/4885CYP3A4 501/4885 |
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | ENTPD5, NT5E, ENTPD1 | ALDH1A1 425/4885CYP2C19 757/4885CYP3A4 1184/4885 |
| US-20190135815-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | GRM5, GRIK5, GRM2 | ALDH1A1 2952/4885CYP2C19 3895/4885CYP3A4 2835/4885 |
| US-10640510-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | GRM5, GRIK5, GRM2 | ALDH1A1 2952/4885CYP2C19 3895/4885CYP3A4 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.