Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634031 | 0.83 | PLCG1 (0.53) | CYP3A4CYP2C9CYP2C19KMT2ACA12 | |
| SCHEMBL19695399 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL27742205 | 0.82 | PSIP1 (0.48) | ALDH1A1KMT2AMAPTHSD11B1NPC1 | |
| SCHEMBL14445541 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL2218966 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL12189513 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL27676339 | 0.74 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL15445196 | 0.74 | GAA (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL28435857 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL16820901 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265437-A1 | RNAi Agents for Inhibiting Expression of Matrix Metalloproteinase 7 (MMP7), Compositions Thereof, and Methods of Use | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2023-08-24 | — | — | US | disclosed |
| US-20170283434-A1 | NK1 ANTAGONISTS | OPKO HEALTH INC (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283434-A1 | NK1 ANTAGONISTS | HRH4, CRHR2, HRH2 | ALDH1A1 1005/4885CYP3A4 880/4885CYP2C9 1322/4885 |
| US-20230265437-A1 | RNAi Agents for Inhibiting Expression of Matrix Metalloproteinase 7 (MMP7), Compositions Thereof, and Methods of Use | MMP7, MMP1, MMP17 | ALDH1A1 2042/4885CYP3A4 4596/4885CYP2C9 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.