Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19483310 | 0.85 | ITGB3 (0.34) | KDM4EALDH1A1ITGB3ITGA2BTDP1 | |
| SCHEMBL19483313 | 0.85 | ITGB3 (0.34) | KDM4EALDH1A1ITGB3ITGA2BTDP1 | |
| SCHEMBL23695701 | 0.83 | CPB2 (0.37) | KDM4EALDH1A1ITGB3ITGA2BTDP1 | |
| SCHEMBL13884310 | 0.82 | FOLH1 (0.40) | FOLH1KDM4EITGB3ITGA2BNOD1 | |
| SCHEMBL26743884 | 0.82 | CPB2 (0.40) | FOLH1NOD1SMN1; SMN2CPB2MEN1 | |
| SCHEMBL18377220 | 0.82 | FOLH1 (0.40) | FOLH1KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL13262513 | 0.82 | FOLH1 (0.40) | FOLH1KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL22309224 | 0.81 | FOLH1 (0.39) | FOLH1KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL24225804 | 0.81 | FOLH1 (0.42) | FOLH1KDM4EALDH1A1NOD1SMN1; SMN2 | |
| SCHEMBL19776895 | 0.80 | NOD1 (0.42) | FOLH1ITGB3ITGA2BNOD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196859-A1 | Novel antibacterial agents | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196859-A1 | Novel antibacterial agents | ENGASE, PEPD, PGLS | FOLH1 75/4885KDM4E 2434/4885ALDH1A1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.