⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10020866 | 0.88 | — | — | |
| SCHEMBL19829569 | 0.84 | CASP2 (0.32) | — | |
| SCHEMBL10033884 | 0.80 | EPHX2 (0.31) | — | |
| SCHEMBL13148613 | 0.77 | — | — | |
| SCHEMBL9799140 | 0.75 | CASP2 (0.31) | — | |
| SCHEMBL14520490 | 0.74 | FAAH (0.35) | — | |
| SCHEMBL24979274 | 0.72 | SLC6A5 (0.37) | — | |
| SCHEMBL12300506 | 0.71 | PGK1 (0.40) | — | |
| SCHEMBL27672 | 0.71 | NAALAD2 (0.38) | — | |
| SCHEMBL786277 | 0.71 | NAALAD2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247692-B2 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-24 | — | — | US | disclosed |