SCHEMBL1444868

SCHEMBL1444868

CCCCC(CC)COC(=O)c1ccc(C)c(C)c1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.64
CYP3A4 P08684 5/20 0.64
CA2 P00918 1/20 0.64
TSHR P16473 5/20 0.60
MAPK1 P28482 4/20 0.60
LMNA P02545 3/20 0.58
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
HSD17B10 Q99714 4/20 0.51
TDP1 Q9NUW8 3/20 0.46
ATM Q13315 1/20 0.46
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010062 0.86 ALDH1A1 (0.65) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL14645865 0.85 ALDH1A1 (0.71) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL600538 0.84 ALDH1A1 (0.65) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL11274168 0.81 ALDH1A1 (0.73) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL14645787 0.81 ALDH1A1 (0.57) ALDH1A1CYP3A4CA2TSHRMAPK1
Bis(2-Ethylhexyl) Phthalate SCHEMBL8397045 0.80 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL2870121 0.80 ALDH1A1 (0.57) ALDH1A1CYP3A4TSHRMAPK1LMNA
SCHEMBL7732291 0.80 TSHR (0.74) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL812195 0.80 ALDH1A1 (0.83) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL2467994 0.80 ALDH1A1 (0.70) ALDH1A1CYP3A4CA2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702571-B2 Adhesive sheet for temporary fixation and method of manufacturing semiconductor device using the same LG CHEM, LTD. (KR) 2023-07-18 US claimed
US-20210171802-A1 ADHESIVE SHEET FOR TEMPORARY FIXATION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME LG CHEM, LTD. (KR) 2021-06-10 US claimed
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 US claimed
EP-0182881-A1 TOPICAL COMPOSITIONS WEINER, Murray (US) 1986-06-04 EP claimed
WO-1986000014-A1 TOPICAL COMPOSITIONS WEINER MURRAY 1986-01-03 WO claimed
US-11702571-B2 Adhesive sheet for temporary fixation and method of manufacturing semiconductor device using the same LG CHEM, LTD. (KR) 2023-07-18 US disclosed
US-11491091-B2 Cooling product SYMRISE AG (DE) 2022-11-08 US disclosed
US-20210171802-A1 ADHESIVE SHEET FOR TEMPORARY FIXATION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME LG CHEM, LTD. (KR) 2021-06-10 US disclosed
US-20210009808-A1 TRANSPARENT RESIN COMPOSITION, TRANSPARENT COATING FILM AND TRANSPARENT RESIN-COATED GLASS SUBSTRATE TORAY INDUSTRIES, INC. (JP) 2021-01-14 US disclosed
CN-107001530-B Polymer and method of making same 株式会社LG化学 2020-10-20 CN disclosed
CN-107207675-B Polymer and method of making same 株式会社LG化学 2020-04-14 CN disclosed
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 US disclosed
US-5204090-A Water insoluble film-forming acrylate copolymer, a polyoxypropylene ether and sunscreen BRISTOL MYERS SQUIBB (US) 1993-04-20 US disclosed
EP-0283165-B1 SKIN CONDITIONING COMPOSITION AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1992-10-28 EP disclosed
US-4976953-A WITH NONGREASY, NONTACKY FEEL THE PROCTER & GAMBLE COMPANY (US) 1990-12-11 US disclosed
EP-0193387-B1 SUNSCREEN COMPOSITIONS AND METHOD OF PROTECTING SKIN THE PROCTER & GAMBLE COMPANY (US) 1990-09-05 EP disclosed
US-4897259-A VINYLPYRROLIDONE-OLEFIN COPOLYMER, EMULSIFIER, SOLVENT BRISTOL-MYERS COMPANY (US) 1990-01-30 US disclosed
US-4810489-A High oil phase pharmaceutical vehicles and sunscreen compositions having waterproof sun protection factors BRISTOL-MYERS COMPANY (US) 1989-03-07 US disclosed
US-4663157-A ACRYLIC ACID-ETHYLENE COPOLYMER THE PROCTOR & GAMBLE COMPANY (US) 1987-05-05 US disclosed
EP-0193387-A2 Sunscreen compositions and method of protecting skin THE PROCTER & GAMBLE COMPANY (US) 1986-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11491091-B2 Cooling product TRPA1, TRPV2, TRPV1 ALDH1A1 37/4885CYP3A4 1402/4885CA2 650/4885
US-20190099342-A1 COOLING PRODUCT TRPA1, TRPV2, NISCH ALDH1A1 40/4885CYP3A4 1073/4885CA2 737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.