SCHEMBL600538

SCHEMBL600538

CCCCC(CC)COC(=O)c1ccc(N)c(C)c1C

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.65
CYP3A4 P08684 6/20 0.65
CA2 P00918 1/20 0.65
TSHR P16473 5/20 0.62
MAPK1 P28482 4/20 0.62
LMNA P02545 3/20 0.60
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
HSD17B10 Q99714 4/20 0.52
TDP1 Q9NUW8 3/20 0.47
ATM Q13315 1/20 0.47
RECQL P46063 1/20 0.40
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
ERAP2 Q6P179 1/20 0.36
LNPEP Q9UIQ6 1/20 0.36
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1444868 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL379118 0.82 ALDH1A1 (0.82) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL17368984 0.81 ALDH1A1 (0.79) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL7732291 0.81 TSHR (0.74) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL11274168 0.80 ALDH1A1 (0.73) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL6010062 0.80 ALDH1A1 (0.65) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL2819271 0.80 LMNA (0.70) ALDH1A1CYP3A4CA2TSHRMAPK1
SCHEMBL4965582 0.79 ALDH1A1 (0.63) ALDH1A1CYP3A4TSHRMAPK1LMNA
Bis(2-Ethylhexyl)Phthalate SCHEMBL29411299 0.79 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2TSHRMAPK1
Bis(2-Ethylhexyl)Phthalate SCHEMBL21733281 0.79 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104921965-B It reduces to the titanium dioxide after the coating of the whitening effect of skin 西姆莱斯股份公司 2019-09-20 CN claimed
EP-1722859-B1 A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR NATURA COSMETICOS SA (BR) 2010-09-08 EP claimed
US-20070269389-A1 Base Composition for Preparing Multi-Functional Formulations for Care and Protection of the Skin and Hair NATURA COSMETICOS S.A. (BR) 2007-11-22 US claimed
EP-1722859-A1 A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR Natura Cosméticos S.A. (BR) 2006-11-22 EP claimed
WO-2005060923-A1 A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR Natura Cosméticos S.A. (BR) 2005-07-07 WO claimed
US-12226500-B2 Method for suppressing adhesion of air harmful substances KAO CORPORATION (JP) 2025-02-18 US disclosed
CN-113939265-B Method for inhibiting adhesion of atmospheric harmful substances 花王株式会社 2024-04-05 CN disclosed
CN-115768419-A Improved methods and compositions for the treatment of prodrugs of chromanccalin 奎拉里斯生物公司 2023-03-07 CN disclosed
US-20220249339-A1 METHOD FOR SUPPRESSING ATTACHMENT OF AIR POLLUTANTS KAO CORPORATION (JP) 2022-08-11 US disclosed
EP-3981384-A1 METHOD FOR SUPPRESSING ATTACHMENT OF AIR POLLUTANTS Kao Corporation (JP) 2022-04-13 EP disclosed
CN-113939265-A Method for inhibiting adhesion of harmful substances to atmosphere 花王株式会社 2022-01-14 CN disclosed
CN-104921965-B It reduces to the titanium dioxide after the coating of the whitening effect of skin 西姆莱斯股份公司 2019-09-20 CN disclosed
US-5160731-A Unsaturated ketones containing ester or amide groups, UVA and UVB absorbers THE PROCTER & GAMBLE COMPANY (US) 1992-11-03 US disclosed
EP-0251398-B1 NOVEL CHROMOPHORES, SUNSCREEN COMPOSITIONS AND METHODS FOR PREVENTING SUNBURN THE PROCTER & GAMBLE COMPANY (US) 1992-08-12 EP disclosed
EP-0255157-B1 NOVEL SUNSCREEN AGENTS, SUNSCREEN COMPOSITIONS AND METHODS FOR PREVENTING SUNBURN THE PROCTER & GAMBLE COMPANY (US) 1992-08-12 EP disclosed
US-5138089-A Absorbs both ultra violet a and b wavelength radiation THE PROCTER & GAMBLE COMPANY (US) 1992-08-11 US disclosed
US-5041282-A Topical application of sunscreen agent THE PROCTER & GAMBLE COMPANY (US) 1991-08-20 US disclosed
US-4999186-A P-aminobenzoic acid derivatives; chromogens THE PROCTER & GAMBLE COMPANY (US) 1991-03-12 US disclosed
US-4937370-A ABSORB UVA AND UVB WAVELENGTH RADIATION THE PROCTER & GAMBLE COMPANY (US) 1990-06-26 US disclosed
EP-0251398-A2 Novel chromophores, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1988-01-07 EP disclosed