Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27338358 | 0.98 | MAPT (0.37) | MAPTHTTHBBALOX15EDNRB | |
| SCHEMBL2934359 | 0.86 | MAPT (0.40) | MAPTHTTHBBALOX15THRB | |
| SCHEMBL1450636 | 0.84 | GABRP (0.34) | MAPTHTTHBBALOX15THRB | |
| SCHEMBL28846735 | 0.80 | GABRP (0.35) | MAPTHTTHBBALOX15GABRP | |
| SCHEMBL28628608 | 0.78 | LMNA (0.30) | EDNRBEDNRAGABRPGABRDGABRA1 | |
| SCHEMBL6778036 | 0.78 | NPSR1 (0.35) | MAPTTHRBMEN1KMT2AALDH1A1 | |
| SCHEMBL17320675 | 0.76 | LMNA (0.46) | MAPTEDNRBEDNRAMEN1KMT2A | |
| SCHEMBL2933046 | 0.76 | GABRP (0.37) | MAPTHTTHBBALOX15MEN1 | |
| SCHEMBL5566400 | 0.75 | KMT2A (0.35) | MAPTHTTHBBALOX15THRB | |
| SCHEMBL9615419 | 0.75 | NPSR1 (0.44) | MAPTMEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118067873-A | Method for detecting impurities in moxifloxacin hydrochloride sodium chloride injection | 华夏生生药业(北京)有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-116606280-A | Fluoroquinolone compound and application thereof in preparation of antibacterial drugs | 广东工业大学 | 2023-08-18 | — | — | CN | claimed |
| CN-114539213-A | Fluoroquinolone compound and preparation method and application thereof | 广东工业大学 | 2022-05-27 | — | — | CN | claimed |
| EP-2398919-B1 | METHOD FOR IDENTIFYING A SUBPOPULATION OF MAMMALIAN CELLS WITH DISTINCTIVE RIBOSOME TRANSLATION PROFILES | UNIV WAYNE STATE (US) | 2018-07-25 | — | — | EP | claimed |
| US-9388405-B2 | Method for identifying a subpopulation of mammalian cells with distinctive ribosome translation profiles | WAYNE STATE UNIVERSITY (US) | 2016-07-12 | — | — | US | claimed |
| EP-1401829-B1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2012-08-22 | — | — | EP | claimed |
| US-20120107828-A1 | METHOD FOR IDENTIFYING A SUBPOPULATION OF MAMMALIAN CELLS WITH DISTINCTIVE RIBOSOME TRANSLATION PROFILES | WAYNE STATE UNIVERSITY (US) | 2012-05-03 | — | — | US | claimed |
| CN-102276528-A | Chemical preparation method of sarafloxacin hydrochloride | XINCHANG HEBAO BIOLOG TECHNOLOGY CO LTD | 2011-12-14 | — | — | CN | claimed |
| JP-4669607-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| WO-2010096594-A2 | METHOD FOR IDENTIFYING A SUBPOPULATION OF MAMMALIAN CELLS WITH DISTINCTIVE RIBOSOME TRANSLATION PROFILES | WAYNE STATE UNIVERSITY (US) | 2010-08-26 | — | — | WO | claimed |
| EP-0610958-A2 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-08-17 | — | — | EP | claimed |
| WO-1993024481-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1993-12-09 | — | — | WO | claimed |
| US-5237060-A | Cyclization; amination | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | claimed |
| EP-0253235-B1 | 1,8-BRIDGED 4-QUINOLONE CARBOXYLIC ACIDS AND MEDICAMENTS CONTANING THEM | BAYER AG (DE) | 1991-01-02 | — | — | EP | claimed |
| US-4859773-A | Preparation of 1,8-bridged 4-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | claimed |
| US-4847375-A | Antibacterial 1,8-bridged 4-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | claimed |
| US-4816451-A | Antibacterial 1,8-bridged 4-quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | claimed |
| US-4725595-A | 1,8-bridged 4-quinolone-3-carboxylic acid antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | claimed |
| CN-86104256-A | 1, the preparation method of 8-bridging 4-quinolone-3-carboxylic-acid | — | 1987-03-18 | — | — | CN | claimed |
| EP-0179239-A2 | 7-(Pyridinyl)-/-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid having antibacterial activity and preparation thereof | STERLING DRUG INC. (US) | 1986-04-30 | — | — | EP | claimed |