Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768344 | 0.83 | KDM4E (0.42) | NPSR1ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL28846735 | 0.79 | GABRP (0.35) | ALDH1A1HSD17B10SMN1; SMN2MAPTLMNA | |
| SCHEMBL2934359 | 0.75 | MAPT (0.40) | ALDH1A1TSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL1444909 | 0.75 | MAPT (0.38) | CYP3A4ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL1450636 | 0.73 | GABRP (0.34) | CYP3A4ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27338358 | 0.73 | MAPT (0.37) | CYP3A4ALDH1A1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL10831199 | 0.69 | CYP3A4 (0.50) | NPSR1CYP3A4RHOAALDH1A1TSHR | |
| SCHEMBL22709898 | 0.67 | PTGS2 (0.45) | NPSR1CYP3A4RHOAALDH1A1TSHR | |
| SCHEMBL29440764 | 0.67 | KDM4E (0.40) | ALDH1A1HSD17B10SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28626875 | 0.67 | ALDH1A1 (0.37) | ALDH1A1TSHRSMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4134055-A | — | — | None | — | — | JP | disclosed |
| JP-H04134055-A | DIALKYLAMINOACRYLIC ACID ALLYL ESTER AND PRODUCTION THEREOF | UBE IND LTD | 1992-05-07 | — | — | JP | disclosed |