Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16367151 | 0.92 | SLC6A2 (0.44) | SLC6A2SLC6A3TAAR1ALDH1A1KDM4E | |
| SCHEMBL3547410 | 0.82 | SLC6A2 (0.45) | SLC6A2SLC6A3TAAR1ALDH1A1KDM4E | |
| SCHEMBL2404071 | 0.82 | TAAR1 (0.62) | SLC6A2SLC6A3TAAR1ALDH1A1KDM4E | |
| SCHEMBL902293 | 0.78 | NOS3 (0.50) | SLC6A2SLC6A3TAAR1ALDH1A1LMNA | |
| SCHEMBL14438317 | 0.77 | SLC6A2 (0.56) | SLC6A2SLC6A3TAAR1ALDH1A1KDM4E | |
| SCHEMBL12074134 | 0.76 | TAAR1 (0.63) | SLC6A2SLC6A3TAAR1ALDH1A1KDM4E | |
| SCHEMBL30229567 | 0.73 | ALDH1A1 (0.45) | SLC6A2SLC6A3ALDH1A1KDM4ERIPK1 | |
| SCHEMBL19795252 | 0.73 | KMT2A (0.54) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL19002822 | 0.73 | OPRM1 (0.69) | SLC6A2SLC6A3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5648981 | 0.73 | SLC6A2 (0.62) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | DPP7, DPP4, DPP3 | SLC6A2 1134/4885SLC6A3 349/4885TAAR1 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.